Liverpool opened up an eight-point lead at the top of the Premier League with an emphatic and hugely impressive 3-1 win over defending champions Manchester City.
The Manchester United midfielders have knee injuries and will miss Champions League matches against Basel and Deportivo Coruna.
Champions Arsenal eased to a comfortable 2-0 home win over Middlesbrough on Saturday, extending their lead at the top of the English premier league to two points.
Liverpool moved into the top five of the English Premier League with a 2-1 victory at relegation-threatened Norwich City.
The English Premier League champions won 1-0 at Newcastle United through a superbly struck volley by skipper Patrick Vieira.
But title rivals Chelsea and Manchester United were held in Saturday's Premiership matches.
A summary of Sunday's action in the Premier League.
Raheem Sterling scored a hat-trick as champions Manchester City made a convincing start to their title defence with a 5-0 win over West Ham United.
The former beat Leeds United 4-1 while Manchester United got the better of Aston Villa 2-1 in the third round of the FA Cup.
West Ham suffer Fabianski injury blow
Premier League leaders Arsenal showed their class as they comfortably beat north London rivals Tottenham Hotspur 2-0 to book a place in the FA Cup fourth round in an electric atmosphere at the Emirates Stadium on Saturday.
The 27-year-old, who has been sidelined since he fractured his hand in February, was originally meant to serve 21 months but earned an exemption when he led South Korea to gold at the 2018 Asian Games.
Former Arsenal and France midfielder Robert Pires, a member of France's 1998 World Cup-winning squad, has announced his retirement from football at the age of 42.
Images from Saturday's action in the Premier League.
Emiliano Martinez said he had always wanted to come to India.
Manchester United have lost 11 of their 27 league matches this campaign, two more than all of last season. The two previous seasons with 12 league losses (2013-14 and 2021-22) led to managerial changes.
'The moment we found a goal it changed everything'
Manchester United are likely to welcome back captain Wayne Rooney from suspension for their visit to Premier League champions Manchester City on Sunday, hoping the striker can add to his record scoring tally in the derby.
Third-placed Aston Villa are the surprise package of the season and Unai Emery's side face relegation-threatened Burnley while fifth-placed Spurs host a resurgent Bournemouth who have 19 points from their last seven games.
Liverpool striker Luis Suarez has been named the top trending football topic of 2013.
Manchester United won 2-1 at Crystal Palace to consolidate fourth spot.
Images from Saturday's action in the Premier League.
Burnley's 0-0 draw at home to Tottenham Hotspur in the Premier League on Sunday completed a profitable weekend for the three clubs bidding to avoid a swift return to the second tier of English football.
Wayne Rooney scored two first half goals to help send Manchester United to a 4-1 win over a spirited Aston Villa on Saturday, temporarily lifting the gloom surrounding David Moyes' dismal first term in charge.
Promoted Bournemouth are still waiting for their first Premier League points after succumbing to a controversial Christian Benteke goal in a 1-0 defeat at Liverpool on Monday.
Harry Kane was hailed as 'unbelievable' after the England striker's 21st and 22nd goals of the season inspired Tottenham Hotspur to a routine win at hapless Aston Villa on Sunday that boosted their Premier League title ambitions.
Villa's chief executive Christian Purslow said 10 first-team players are among 14 positive cases of coronavirus at the club.
IMAGES from the English Premier League matches played on Wednesday.
Chelsea's commanding start to the Premier League season continued with a 3-0 victory over Aston Villa on Saturday as their rivals for the title continued to look vulnerable.
Manchester City took another decisive step toward an unprecedented fourth successive Premier League title with a 4-0 demolition of Fulham.
IMAGES from football matches played across European leagues on Saturday
IMAGES from the English Premier League matches played on Sunday.
Manchester City manager Pep Guardiola accused Sadio Mane of diving after the Liverpool forward's match-winning display against Aston Villa in the English Premier League.
A summary of sports events and sports persons, who made news on Friday.
Aston Villa and Sheffield United players and referee Michael Oliver took a knee at kickoff in support of the "Black Lives Matter" movement as the Premier League season restarted